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Abstract ［Objectives］ This study was conducted to analyze the Raphanus sativus L. medicinal materials from different origins and batches in Guizhou Province to explore its quality standards.
［Methods］The plant morphology, material shape and microscopic characteristics of R. sativus were identified; and qualitative identification was performed by the TLC method.
［Results］ The plant morphology, material shape and microscopic characteristics of the R. sativus medicinal materials were described; and the TLC identification method of the R. sativus medicinal materials was established, with clear spots, good separation, and good specificity.
［Conclusions］The method is accurate, simple, highly sensitive, interference-free, has good reproducibility, and can be used as a data support for the formulation of quality standards for R. sativus medicinal materials.
Key words Raphanus sativus L.; Medicinal materials; Quality standard; Determination
Received: December 12, 2020 Accepted: February 21, 2021
Supported by Science and Technology Innovation Platform Construction Project of Anshun City (ASKP［2017］03); Anshun Traditional Chinese Medicine (Ethnic Medicine) Inspection Technology Innovation Talent Team (ASKC［2018］09).
Feng BAO(1963-), male, P. R. China, pharmacist-in-charge, devoted to research about drug inspection and quality standards.
*Corresponding author. E-mail: 826735176@qq.com.
Raphanus sativus L. was first published in "Supplements to Compendium of Materia Medica", saying: "When cutting R. sativus, the remaining ones are left in the ground, thin and fleshless, old and stringy, like a skeleton, and thus named Kuluobo. It can ventilate the lung qi, and can be used for relieving gas poisoning." Compendium of Materia Medica records: "R. sativus is commonly cultivated today. It is planted in June, harvested for the aboveground part in autumn, and dug for roots in winter. The plants bolt highly and show small purple flowers in late spring, and siliques are formed in early summer. The seeds are as big as marijuana seeds, with varying lengths and yellow-red colors. The large leaves are like turnips, and the thin ones have fine pubescence. The roots are red or white, and their shapes are long or round." Compilation of Medical Records (Yizong Huibian) records its use for treating jaundice, which is also recorded in later pharmacy books.
In Guizhou, the ancestors of the Miao and Buyi peoples had the habit of using R. sativus to treat gastric diseases for a long time. On this basis, they developed Xianrenzhang Weikang Capsules and other patent medicines, which are widely used national medicines in our province, and are included in the 2003 edition of Quality Standards for Traditional Chinese Medicines and Ethnic Medicines in Guizhou Province. The original standard has few inspection items and lacks characteristic identification and quality control indexes, and the local standards of R. sativus medicinal materials need to be improved and perfected. Up to now, there are no detailed and systematic reports on the quality standards of R. sativus. Therefore, to study and improve the quality standards of the medicinal material and to provide plans and data support for the formulation of more reasonable, scientific, comprehensive and controllable statutory medicinal material standards have clear practical significance.
［Methods］The plant morphology, material shape and microscopic characteristics of R. sativus were identified; and qualitative identification was performed by the TLC method.
［Results］ The plant morphology, material shape and microscopic characteristics of the R. sativus medicinal materials were described; and the TLC identification method of the R. sativus medicinal materials was established, with clear spots, good separation, and good specificity.
［Conclusions］The method is accurate, simple, highly sensitive, interference-free, has good reproducibility, and can be used as a data support for the formulation of quality standards for R. sativus medicinal materials.
Key words Raphanus sativus L.; Medicinal materials; Quality standard; Determination
Received: December 12, 2020 Accepted: February 21, 2021
Supported by Science and Technology Innovation Platform Construction Project of Anshun City (ASKP［2017］03); Anshun Traditional Chinese Medicine (Ethnic Medicine) Inspection Technology Innovation Talent Team (ASKC［2018］09).
Feng BAO(1963-), male, P. R. China, pharmacist-in-charge, devoted to research about drug inspection and quality standards.
*Corresponding author. E-mail: 826735176@qq.com.
Raphanus sativus L. was first published in "Supplements to Compendium of Materia Medica", saying: "When cutting R. sativus, the remaining ones are left in the ground, thin and fleshless, old and stringy, like a skeleton, and thus named Kuluobo. It can ventilate the lung qi, and can be used for relieving gas poisoning." Compendium of Materia Medica records: "R. sativus is commonly cultivated today. It is planted in June, harvested for the aboveground part in autumn, and dug for roots in winter. The plants bolt highly and show small purple flowers in late spring, and siliques are formed in early summer. The seeds are as big as marijuana seeds, with varying lengths and yellow-red colors. The large leaves are like turnips, and the thin ones have fine pubescence. The roots are red or white, and their shapes are long or round." Compilation of Medical Records (Yizong Huibian) records its use for treating jaundice, which is also recorded in later pharmacy books.
In Guizhou, the ancestors of the Miao and Buyi peoples had the habit of using R. sativus to treat gastric diseases for a long time. On this basis, they developed Xianrenzhang Weikang Capsules and other patent medicines, which are widely used national medicines in our province, and are included in the 2003 edition of Quality Standards for Traditional Chinese Medicines and Ethnic Medicines in Guizhou Province. The original standard has few inspection items and lacks characteristic identification and quality control indexes, and the local standards of R. sativus medicinal materials need to be improved and perfected. Up to now, there are no detailed and systematic reports on the quality standards of R. sativus. Therefore, to study and improve the quality standards of the medicinal material and to provide plans and data support for the formulation of more reasonable, scientific, comprehensive and controllable statutory medicinal material standards have clear practical significance.