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目的 观察磷化氢毒性动物实验病理变化。方法 ３６ 只家兔，雌雄不拘，随机将１６ 只置于施用磷化铝的粮仓，１６ 只置于农户，４ 只作对照。磷化氢浓度仓库为１４９ ～８１ ｍｇ／ ｍ ３ ，农户为３８６ ～０１ｍ ｇ／ ｍ ３ 。结果 病理改变为喉和气管粘膜１００ ％ 有重度血管扩张充血，水肿及少数炎细胞浸润，２５ ％ 有轻度变性坏死及脱落。肺均有充血改变，肝、脾、心、肾及脑膜血管扩张充血，部分肝细胞有胞浆疏松及水样变性。染毒脱离后家兔的病理改变，１ 周后明显减轻，２ 周后各器官组织基本恢复正常。结论 磷化氢对动物呼吸道有直接损害作用。
Objective To observe the pathological changes of phosphine toxicity animals. Methods Thirty-six rabbits were randomly assigned to male and female rabbits. Sixteen randomly placed granaries with aluminum phosphide, 16 were housed in rural households and four were used as controls. The concentration of phosphine in the warehouse ranged from 149 to 81 mg / m 3 and that of farmers from 386 to 01 m g / m 3. Results Pathological changes of throat and tracheal mucosa 100% have severe vasodilation congestion, edema and a small number of inflammatory cell infiltration, 25% of mild degeneration and necrosis and shedding. Lung congestion have changed, liver, spleen, heart, kidney and meninges vascular dilatation and congestion, some of the hepatocytes loose cytoplasm and degeneration of water samples. The pathological changes of rabbits after exposure to radiation were significantly alleviated after 1 week and returned to normal after 2 weeks. Conclusion Phosphine has a direct impact on animal respiratory tract.