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目的:探讨上呼吸道感染患者发热程度与自身热源性因子的相关性。方法:随机选取180名就诊号为单数的上呼吸道感染伴发热患者,记录就诊时体温并依据体温分为低热组、中度发热组以及高热组,分别检测各组患者IL-1、IL-6、TNF-α、IL-10水平,比较各组患者的IL-1、IL-6、TNF-α、IL-10水平之间是否存在差异。结果:不同发热程度组别患者IL-1、IL-6、TNF-α、IL-10水平存在差异(P<0.05或P<0.01),其中高热组患者IL-1、IL-10水平与低热组的差异尤为明显(P<0.01)。结论:上呼吸道感染伴发热患者的热源性因子水平与其体温存在相关性。对上呼吸道感染发热患者热源性因子的追踪检测与分析,能及时、较好地对患者疾病发展趋势及预后进行准确评估。且其操作安全、简便,值得临床推广应用。
Objective: To investigate the correlation between the degree of fever in patients with upper respiratory tract infection and their own heat-derived factors. Methods: A total of 180 patients with upper respiratory tract infection and fever were enrolled in this study. Body temperature was recorded and divided into low fever group, moderate fever group and high fever group according to body temperature. IL-1, IL-6 , TNF-α, IL-10 levels were compared between groups of patients with IL-1, IL-6, TNF-α, IL-10 levels between the differences. Results: The levels of IL-1, IL-6, TNF-α and IL-10 in patients with different fever groups were significantly different (P <0.05 or P <0.01). The levels of IL-1 and IL- The differences between groups were particularly significant (P <0.01). Conclusion: There is a correlation between the level of heat-induced factor in upper respiratory tract infection with fever and the body temperature. Follow-up detection and analysis of heat-derived factors in fever patients with upper respiratory tract infection can accurately and accurately evaluate the patient’s disease development trend and prognosis in a timely and good manner. And its operation is safe and easy, it is worth clinical promotion and application.