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目前,应用功能性电刺激(functional electrical stimulation,FES)进行中风后康复治疗已经十分普遍,但是对于FES治疗过程中大脑的状态变化却缺乏深入的研究.掌握这一变化规律有助于了解大脑在FES治疗过程中的康复机制.笔者尝试通过研究FES诱发的脑电信号,探究在治疗过程中大脑的脑电特征变化.结合FES设计了主动、被动模式(人工被动和刺激下被动)下的下肢运动实验,采集了6名受试者(4名中风患者和2名健康受试者)的数据,并利用时频分析和源定位等方法对数据进行分析.结果发现在多种实验模式下正常受试者与患者的脑电信号中均存在事件相关去同步(event-related desynchronization,ERD)现象,证实了中风患者受损后的大脑区域仍然能够被激活;在电刺激模式下ERD的强度随电刺激的增强而增大,表明适当的高强度电刺激可以为大脑提供更好的激活作用;通过源定位分析发现感觉运动区的激活在动作期较强,而在动作保持期内激活效应较差.研究结果将有助于加深认识FES对大脑的激励作用,同时为医师设计康复治疗方案提供可靠依据.
At present, the use of functional electrical stimulation (FES) for post-stroke rehabilitation is very common, but there is a lack of in-depth study on the state of the brain during the FES treatment.Taking this rule of thumb helps to understand the role of the brain FES treatment rehabilitation process.The author attempts to study the EEG signals induced by FES to explore the brain during EEG changes in the treatment process.According to FES designed active and passive mode (artificial passive and passive stimulation) of the lower extremities In the exercise test, data from 6 subjects (4 stroke patients and 2 healthy subjects) were collected and analyzed by time-frequency analysis and source localization, etc. The data were found to be normal under various experimental modes There is event-related desynchronization (ERD) in both EEG signals of subjects and patients, confirming that the damaged brain regions of stroke patients can still be activated. The intensity of ERD in electrical stimulation Increased electrical stimulation increased, indicating that appropriate high-intensity electrical stimulation can provide better activation of the brain; found by the source localization analysis found that feeling Activation of the active area in the action of the strong, and remain active during bad effect in action. The results will help to deepen understanding FES incentive effect on the brain, at the same time provide a reliable basis for the design of a physician rehabilitation program.