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目的探讨丙泊酚复合舒芬太尼用于妇科门诊无痛人流的安全性和有效性。方法 ASAⅠ-Ⅱ级门诊无痛人流的检查患者80例,年龄18-42岁,体重44-78kg,随机分为两组,即丙泊酚+生理盐水组(P组)、丙泊酚复合舒芬太尼组(PS组),每组40例,各组在静脉推注丙泊酚前分别注入生理盐水2ml、舒芬太尼0.15-0.2ug/kg,待患者睫毛反射消失、呼之不应时放入窥阴器。人流过程中持续监测HR、MAP、SPO_2并记录丙泊酚的量,意识及定向力恢复时间、人流操作时间等。结果两组患者中HR、MAP、SPO_2与术前或术后相比有明显降低(P<0.05)。意识恢复时间P组与PS组相比明显延长,差异有统计学意义(P<0.05)。丙泊酚用量P组比PS组增加差异有统计学意义(P<0.05)。结论丙泊酚复合小剂量舒芬太尼不仅可以减少丙泊酚的用量,有效降低呼吸抑制等副作用,而且能缩短苏醒时间,使麻醉更加平稳。
Objective To investigate the safety and efficacy of propofol combined with sufentanil in painless gynecology clinic. Methods A total of 80 patients with ASAⅠ-Ⅱdetector painless examination, aged 18-42 and weighing 44-78kg, were randomly divided into two groups: propofol + saline group (P group), propofol combined Shu Shu Fentanyl group (PS group), 40 cases in each group before injection of propofol intravenous infusion of 2ml, Sufentanil 0.15-0.2ug / kg, until the patient’s eyelash reflex disappeared, the call is not Should be placed into the vagina. The process of continuous monitoring of HR, MAP, SPO_2 and record the amount of propofol, awareness and orientation recovery time, flow of time and so on. Results The HR, MAP and SPO 2 in both groups were significantly lower than those before operation or postoperatively (P <0.05). Consciousness recovery time P group was significantly longer than the PS group, the difference was statistically significant (P <0.05). Propofol dosage increased significantly in P group than PS group (P <0.05). Conclusion Propofol combined with low-dose sufentanil can not only reduce the dosage of propofol, effectively reduce the side effects such as respiratory depression, but also shorten the recovery time, make anesthesia more stable.