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目的探讨甲基强的松龙用于慢性阻塞性肺病急性加重期的疗效。方法回顾分析95例患者的临床资料。结果 95例使用糖皮质激素,采用阶梯疗法,从静脉滴注甲基泼尼松龙渐减量至口服泼尼松。经精心治疗后,本组54例静息状态下咳喘、呼吸困难、发绀明显减轻或消失,水肿、肺部音消失;35例上述症状及体征减轻;6例治疗前后病情无变化、加重或死亡,其中死亡2例,死因呼吸衰竭1例和感染性休克1例。结论 COPD急性加重期病情是多种多样的,提高COPD急性加重治疗效果对于改善COPD患者的预后和生命质量具有重要意义。
Objective To investigate the efficacy of methylprednisolone for acute exacerbation of chronic obstructive pulmonary disease. Methods The clinical data of 95 patients were retrospectively analyzed. Results 95 cases of glucocorticoid, the use of step therapies, gradual reduction of methylprednisolone from intravenous to oral prednisone. After careful treatment, the group of 54 cases of cough and whey at rest, breathing difficulties, cyanosis significantly reduced or disappeared, edema, lung tone disappeared; 35 cases of the above symptoms and signs reduced; 6 cases before and after the disease did not change, aggravate or Death, including 2 deaths, 1 death from respiratory failure and 1 septic shock. Conclusions The condition of acute exacerbation of COPD is varied, and improving acute exacerbation of COPD is of great significance for improving the prognosis and quality of life of COPD patients.