多发性骨髓瘤 ( MM)是浆细胞异常增生的恶性肿瘤 ,近年来发病率有增多趋势 ,但其起病隐匿 ,临床表现复杂多样 ,极易产生漏诊、误诊。我院自 1990年至 1998年 8月共收治 5 2例 ,全部病例经骨髓检查 ,局部肿块活检 ,蛋白电泳 ,免疫球蛋白及 X线等检查 ,确诊为多发性骨髓瘤 ,其中 Multiple myeloma (MM) is a malignant tumor of plasma cell dysplasia. In recent years, the incidence has increased. However, its onset is occult, clinical manifestations are complex and diverse, and missed diagnosis and misdiagnosis can easily occur. In our hospital from 1990 to August 1998, a total of 52 cases were treated. All cases were examined by bone marrow, local mass biopsy, protein electrophoresis, immunoglobulins, and X-ray examinations. The diagnosis was multiple myeloma.