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本文作者研究了乙型肝炎疫苗(HBV)与DTP-脊髓灰质炎疫苗(DTP-P)的相互作用。实验用疫苗均来自巴斯德研究所,接种对象是塞内加尔农村3～24月龄婴幼儿,将其分为3组:组Ⅰ,48人,首次注射时平均年龄为11.0月龄,仅接种HBV,于0和6个月各接种1针,12个月时加种1针。组Ⅱ,29人,平均年龄为7.5月龄。首次注射DTP-P和BCG,第6和12个月时只注射DTP-P。组Ⅲ,108人,平均年龄为11.7月龄。第1次注射DTP-P、BCG和HBV,第6和12个月时注射DTP-P和HBV。于0、6和12个月时采集血样,用放射免疫试验测定抗体滴度。抗毒素以国际抗毒素单位(IAU)/ml表示,抗-HBs效价以mIU/
The authors studied the interaction of Hepatitis B vaccine (HBV) with DTP-polio vaccine (DTP-P). The experimental vaccines were all from Pasteur Institute. The vaccinated subjects were infants from 3 to 24 months of age in rural Senegal. The vaccinated rabbits were divided into three groups: group I and group 48, with an average age of 11.0 months after first injection and only HBV , Inoculation of 1 needle at 0 and 6 months and 1 needle at 12 months. Group Ⅱ, 29 people, the average age of 7.5 months. DTP-P and BCG were injected for the first time, and only DTP-P was injected at 6 and 12 months. Group Ⅲ, 108 people, the average age of 11.7 months. DTP-P, BCG and HBV were injected first and DTP-P and HBV were injected at 6 and 12 months. Blood samples were collected at 0, 6 and 12 months and antibody titers were determined by radioimmunoassay. Antitoxin is expressed in International Antitoxin Unit (IAU) / ml and anti-HBs titer is in mIU /