目的观察结肠镜检查前短时间内口服电解质液与甘露醇清洁肠道的效果,以利于选择合适的药物对不同的患者行肠道准备。方法对278例口服电解质液(A组)和224例口服甘露醇(B组)行肠道清洁的患者服药时间、排便情况、清肠效果及副作用进行统计分析,观察两种方法在2～5 h内的清洁效果及副作用。结果两组在2～5h内均能达到良好的清洁效果。①两组肠道清洁方法的效果总合格率分别为86.33%和87.50%,无明显差异(P>0.05)。②两组排便情况比较:第一次排便时间两组无差异(P>0.05);排出物为清水或黄水时间及最后一次排便时间A组早于B组(P<0.05);排便总次数A组少于B组(P<0.05)。③两组受检者均未发生严重不良反应,两组总的不良反应无统计学差异(P>0.05);主要的副作用为呕吐、腹痛、腹胀、头昏、乏力、饥饿感等,和传统提前准备时相比没有差别。结论用上述两种方法在当天上午8:00～11:00开始服药准备,在10:00～16:00之间可根据排便情况安排当日检查,方便患者,宜于推广。 Objective To observe the effect of oral administration of electrolyte solution and mannitol on intestinal tract in a short time before colonoscopy to facilitate the selection of suitable drugs for intestinal preparation in different patients. Methods The time, defecation, bowel function and side effects of intestinal cleaning in 278 oral electrolyte solutions (group A) and 224 oral mannitol (group B) were statistically analyzed. The results of two methods were analyzed in 2 ~ 5 h within the cleaning effect and side effects. Results Both groups can achieve a good cleaning effect in 2 ~ 5h. ① The total pass rate of two groups of intestinal cleaning methods were 86.33% and 87.50% respectively, with no significant difference (P> 0.05). ② Comparison of defecation between the two groups: there was no difference in the first defecation time between the two groups (P> 0.05); the effluent was clear water or yellow water time and the last defecation time was earlier in group A than in group B (P <0.05) Group A was less than group B (P <0.05). ③ The two groups of patients had no serious adverse reactions, the two groups had no significant difference in the total adverse reactions (P> 0.05); the main side effects were vomiting, abdominal pain, bloating, dizziness, fatigue, hunger, etc., There is no difference when preparing in advance. Conclusions With the above two methods in the morning 8: 00 ~ 11: 00 start taking medication preparation, between 10: 00 ~ 16: 00 can be arranged according to the situation of defecation on the same day to facilitate the patient, it is appropriate to promote.