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目的:通过头部核磁共振(MRI)检查,研究新生儿脑损伤的病理生理改变,提高新生儿脑损伤早期诊断率,从而及时治疗,正确评估疾病的预后,为临床治疗提供了可靠的影像资料和依据。方法:回顾分析本院新生儿病房收治的20例临床疑诊有新生儿脑损伤患儿的临床资料,全部病例均进行常规头部MRI及DWI扫描。结果:20例新生儿通过头部核磁检查发现脑损伤17例(阳性率85%),其中新生儿缺氧缺血性脑病10例(占50%),早产儿脑白质损伤4例(占20%),颅内出血1例(占5%),胼胝体发育异常2例(占10%),正常3例(占15%)。结论:常规MRI可以明确新生儿脑损伤病灶的部位、范围、性质及与周围结构的关系。DWI对于脑细胞缺氧缺血的反应更灵敏和特异。尤其MRI检查无X线辐射,对正处在高度发育阶段新生儿来说将更具安全性,可在新生儿脑损伤早期诊断中推广。
OBJECTIVE: To study the pathophysiological changes of neonatal brain injury through head MRI and to improve the early diagnosis rate of neonatal brain injury so as to timely treat and correctly evaluate the prognosis of the disease, so as to provide reliable imaging data for clinical treatment And based on. Methods: The clinical data of 20 neonates with suspected neonatal brain injury admitted to neonatal wards in our hospital were retrospectively analyzed. All patients underwent MRI and DWI. Results: Twenty cases of brain injury were found in 20 neonates (the positive rate was 85%) by head magnetic resonance imaging. Among them, 10 cases were hypoxic-ischemic encephalopathy (50%), 4 were white matter damage in preterm infants (20% ), Intracranial hemorrhage in 1 case (5%), corpus callosum in 2 cases (10%) and normal in 3 cases (15%). CONCLUSION: Conventional MRI can clarify the location, extent, nature and the relationship with the surrounding structures of neonatal brain lesions. DWI is more sensitive and specific to the response of brain cells to hypoxia-ischemia. In particular, MRI examination without X-ray radiation is more safe for newborns who are in the high developmental stage and can be popularized in the early diagnosis of neonatal brain injury.