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We have reviewed the role of nitric oxide(NO)in the Apoptosis in cardiomyocytes.NO is a highly reactivesignaling molecule produced normally in the heart and is an important modulator of myocardial function.The apoptosisprocess has two main pathways,the death receptor pathway and the mitochondria-dependent pathway.NO is an impor-tant regulator of apoptosis within the mammalian system,capable of both inducing and preventing apoptosis,dependingupon the level of NO production and environmental milieu.
We have reviewed the role of nitric oxide (NO) in the Apoptosis in cardiomyocytes. NO is a highly reactive signaling molecule produced normally in the heart and is an important modulator of myocardial function. The apoptosis process has two main pathways, the death receptor pathway and the mitochondria-dependent pathway. NO is an impor-tant regulator of apoptosis within the mammalian system, capable of both inducing and preventing apoptosis, depending on the level of NO production and environmental milieu.