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目的分析高活性抗逆转录病毒疗法(HAART)联合康艾治疗对人类免疫缺陷病毒(HIV-1)患者病毒载量及CD_4~+T细胞的影响。方法选取医院2012年1月-2016年1月收治的60例HIV-1阳性患者,通过随机数字表法分为观察组30例与对照组30例,对照组接受高活性抗逆转录病毒疗法,观察组采用高活性抗逆转录病毒疗法联合康艾注射液治疗,探讨两组患者的临床疗效、病毒载量及CD_4~+T细胞的变化。结果观察组总有效率93.33%,明显高于对照组的83.33%;治疗6周后、随访6个月,观察组患者病毒载量水平明显低于对照组,差异有统计学意义(P<0.05);治疗6周后、随访6个月,观察组患者CD_4~+T细胞水平,明显高于对照组,差异有统计学意义(P<0.05)。结论针对HIV-1阳性患者,采用高活性抗逆转录病毒疗法联合康艾治疗,病毒载量、CD_4~+T细胞情况好转,有利于增强机体免疫力,提高治疗效果,改善患者生活质量,值得临床推广应用。
Objective To analyze the effect of HAART combined with Kangai treatment on viral load and CD_4 ~ + T cells in human immunodeficiency virus (HIV-1) patients. Methods Sixty HIV-1 positive patients admitted to our hospital from January 2012 to January 2016 were divided into observation group (30 cases) and control group (30 cases) by random number table. The control group received high activity antiretroviral therapy The observation group was treated with highly active antiretroviral therapy combined with Kangai injection, and the clinical efficacy, viral load and the changes of CD_4 ~ + T cells in both groups were observed. Results The total effective rate in the observation group was 93.33%, which was significantly higher than that in the control group (83.33%). After 6 weeks of treatment and 6 months of follow-up, the viral load in the observation group was significantly lower than that in the control group (P <0.05 ). After 6 weeks of treatment and 6 months of follow-up, the level of CD_4 ~ + T cells in the observation group was significantly higher than that in the control group (P <0.05). Conclusions HIV-1-positive patients with high activity of antiretroviral therapy combined with Kang Yi treatment, viral load, CD_4 ~ + T cells improved, help to enhance the body immunity, improve the therapeutic effect and improve the quality of life of patients, it is worth Clinical application.