Investigation of diagnosis and treatment of hemolysis-elevated liver enzymes-low platelet counts (HE

来源 :中华医学杂志(英文版) | 被引量 : 0次 | 上传用户:junwen2009
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background Hemolysis-elevated liver enzymes-low platelet counts (HELLP) syndrome is a clinical condition occurring in middle and late stage pregnancy.It is characterized by hemolysis, elevated liver enzymes and low platelet counts.This study involves the analysis of the diagnosis, clinical characteristics and treatment of 59 cases of HELLP syndrome as well as the clinical classification, method of delivery and gestational age at delivery.Methods Clinical data from 59 cases of HELLP syndrome occurring from January 2000 to December 2009 were analyzed retrospectively.Thirty-five cases were classified as complete HELLP syndrome and 24 cases were considered partial HELLP syndrome.Results Twenty-six of the 59 analyzed patients (44%) with complete HELLP syndrome showed rapid onset, severe signs, symptoms, and complications in addition to a poor clinical outcome.Complications included multiple organ dysfunction syndrome (MODS) occurring in 18 cases, eclampsia (3 cases), placental abruption (3 cases), and perinatal death (4 cases).The remaining 33 cases (24 with partial and 9 with complete HELLP) were characterized by less severe signs, symptoms, complications and progression of the condition.Two of these cases were complicated with MODS (6.1%), and 1 with perinatal death (3.0%).Twelve non-radical-type cases received conservative treatment.The remaining 4 patients had recurring HELLP syndrome (6.78%).Conclusions HELLP syndrome is classified as the radical type and non-radical-type according to clinical characteristics and outcome.Classification of HELLP syndrome cases according to clinical features can help in the monitoring and treatment of the disease.Active termination of pregnancy should be considered for radical-type cases.Non-radical-type cases can undergo conservative treatment with close monitoring in an attempt to improve perinatal outcome without increasing matal morbidity.
其他文献
目的研究急性脑梗死患者脑缺血的部位、面积大小与消化道出血率及死亡率的关系。方法对1892例急性脑梗死按脑缺血部位、面积大小,分别比较消化1892例急性脑梗死按脑缺血部位分
澄城县耕地面积 87万亩,总人口 37.7万人。县境内降雨稀少,十年九旱,水资源人均、亩均占有量仅为 440.3立方米和 190.8立方米,分别占全省平均水平的三分之一和四分之一,尚不足全国
本届500强销售收入总额达2.62万亿元,同比增长34.9%,体现了我国化工企业综合实力和竞争力不断提升。根据统计数据:2012中国化工企业500强榜单中营业收入超过300亿元的企业有7家;200-
期刊
介绍苯并咪唑酮颜料的种类与其结构式,研讨不同的合成方法与颜料的应用领域,对颜料蓝80的介绍。