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目的探讨远端胃癌根治术后早期经口进食的可行性、安全性及术后早期康复情况。方法将2009年5月2011年1月收治的62例远端胃癌根治术患者随机分为早期经口进食(early oral feeding,EOF,30例)组及传统进食(traditional feeding,TF,32例)组。比较两种营养支持方法对患者术后并发症、胃肠功能恢复及血清蛋白的影响。结果 EOF组术后早期经口进食耐受率达90%(27/30),两组术后并发症发生率相比差异无统计学意义(χ2=0.046,P=0.830)。EOF组术后首次肛门排气及排便时间均早于TF组(P=0.000)。术后8d时EOF组血清前清蛋白和转铁蛋白明显高于TF组(P=0.028,0.013)。结论远端胃癌根治术后早期经口进食是安全、可行的,能促进患者的早期恢复。
Objective To investigate the feasibility, safety and early postoperative recovery of early oral intake of distal gastric cancer after radical operation. Methods Sixty-two patients with distal gastric cancer who underwent radical surgery in May 2009 and January 2011 were randomly divided into three groups: early oral feeding (EOF, 30 cases) and traditional feeding (TF, 32 cases) group. The effects of two nutritional support methods on postoperative complications, gastrointestinal function recovery and serum proteins were compared. Results The early postoperative oral tolerance rate of EOF group was 90% (27/30). There was no significant difference in the incidence of postoperative complications between the two groups (χ2 = 0.046, P = 0.830). The mean time to first anal exhaust and defecation in the EOF group was earlier than that in the TF group (P = 0.000). At 8 days after operation, serum prealbumin and transferrin in EOF group were significantly higher than those in TF group (P = 0.028,0.013). Conclusion Early oral gavage of distal gastric cancer is safe and feasible and can promote the early recovery of patients.