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目的:分析低度恶性肺黏液表皮样癌的诊断、发病年龄、影像学特点、临床特点、外科治疗、随访及预后情况。方法:回顾总结5例手术切除的原发性肺黏液表皮样癌,行肺叶切除术3例,肺叶切除加支气管袖状切除1例,肺楔形切除1例,并分析其临床特征。结果:5例术前经影像学检查均确诊为恶性肿瘤,3例中央型术前行纤支镜检查,其中1例考虑肺黏液细胞癌,l例查出癌细胞,1例未查出癌细胞。4例完全切除病例均未发现淋巴结转移。术后随访l、3、5年生存率均为100%。结论:低度恶性肺黏液表皮样癌经彻底手术切除可获治愈。
Objective: To analyze the diagnosis, age of onset, imaging features, clinical features, surgical treatment, follow-up and prognosis of low grade malignant lung mucoepidermoid carcinoma. Methods: Five cases of resected primary lung mucoepidermoid carcinoma were retrospectively reviewed. Three cases underwent lobectomy, one case underwent lobectomy plus bronchial sleeve resection, and one case underwent wedge resection. The clinical features were analyzed. Results: Five cases were diagnosed as malignant tumor by imaging before operation. Three cases of central type were diagnosed by bronchofiberscopy. Among them, one case considered lung mucinous cell carcinoma, one case detected cancer cells and one case did not detect carcinoma cell. No lymph node metastasis was found in 4 cases of complete resection. Follow-up l, 3, 5-year survival rates were 100%. Conclusions: Low grade malignant lung mucoepidermoid carcinoma can be cured by complete surgical resection.