Objective To describe two clinical cases involving patients who were administered800 IU of h CG to trigger oocyte maturation and who underwent a frozen-thawed embryo transfer(FET) cycle.Methods Two infertile patients with high ovarian response undergoing stimulation for IVF, in which 800 IU of h CG was injected by mistake. IVF patients treated under a short protocol with 800 IU of h CG triggering ovulation. Live birth, clinical pregnancy outcomes and ovarian hyperstimulation syndrome(OHSS) were observed.Results Neither cycle of the two patients was canceled for oocyte retrieval failure and no OHSS was observed. Both patients gave birth to live twins after FET.Conclusion Triggering oocyte maturation in two hyper-responders by employing800 IU of hC G could produce a good quantity of good-quality oocytes and an excellent clinical pregnancy and retain the opportunity for conception and live birth. Broader studies are needed. Objective To describe two clinical cases involving patients who were administered800 IU of h CG to trigger oocyte maturation and who underwent a frozen-thawed embryo transfer (FET) cycle. Methods Two infertile patients with high ovarian response undergoing stimulation for IVF, in which 800 IU of h CG was injected by mistake. IVF patients treated under a short protocol with 800 IU of h CG triggering ovulation. Live birth, clinical pregnancy outcomes and ovarian hyperstimulation syndrome (OHSS) were observed. Results Neither cycle of the two patients was canceled for Both patients gave birth to live twins after FET. Confusion Triggering oocyte maturation in two hyper-responders by employing 800 IU of hC G could produce a good quantity of good-quality oocytes and an excellent clinical pregnancy and retain the opportunity for conception and live birth. Broader studies are needed.