目的:探讨双源CT全脑灌注成像后处理大脑中动脉不同监测位置对灌注成像参数的影响。方法:回顾性分析本溪市中心医院2019年3月至2020年1月行全脑CT灌注成像检查患者35例的双源CT全脑灌注成像资料，每例数据进行3次图像后处理，分别选取颈内动脉C1段、大脑中动脉M1段、大脑中动脉M2段作为输入动脉的监测位置。取右侧颞极连续3个层面绘制感兴趣区(ROI)，测量全脑灌注成像的脑血流量(CBF)、脑血容量(CBV)、平均通过时间(MTT)、排空时间(TTD)，取3个层面的平均值，采用自身对照研究进行分析。结果:监测位置为C1的各个灌注参数分别为CBF(75.699±15.491)mL·100 mLn －1·minn －1、CBV(4.892±0.725)mL/100 mL、MTT(4.375±0.745)s、TTD(3.926±1.049)s；监测位置为M1的各个灌注参数分别为CBF(74.219±12.722)mL·100 mLn －1·minn －1、CBV(4.982±1.072)mL/100 mL、MTT(4.475±0.871)s、TTD(4.115±1.164)s；监测位置为M2的各个灌注参数分别为CBF(71.431±14.743)mL·100 mLn －1·minn －1、CBV(4.797±1.021)mL/100 mL、MTT(4.620±0.936)s、TTD(4.105±1.249)s。监测位置为C1与M1间的各灌注参数差异均无统计学意义(均n P>0.05)。监测位置C1与M2间的CBF、MTT参数差异均有统计学意义(CBF：n t＝2.600，n P0.05). When C1 and M2 segment were regarded as the monitor locations, there were statistically significant differences in CBF and MTT between them(CBF:n t=2.600, n P<0.05; MTT:n t=-2.510, n P0.05). When M1 and M2 segment were regarded as the monitor locations, there were statistically significant differences in CBF and MTT between them(CBF:n t=2.277, n P<0.05; MTT:n t=-2.371, n P0.05).n Conclusion:Choosing different monitor locations of input artery has influence on the parameters of CT whole brain perfusion imaging.Therefore, in the reconstruction of cerebral CT perfusion, the monitor location of input artery should select C1 segment of internal carotid artery or M1 segment of middle cerebral artery.