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恶性黑色素瘤(Malignant Melanoma)是一种起源于神经嵴黑色素细胞的高度恶性肿瘤,90%原发于皮肤,也好发于接近皮肤的黏膜、脉络膜、软脑膜和眼睛等处~[1]。原发于消化道者罕见,占消化道恶性肿瘤的1%~3%~[2],曾被认为是转移性的,现研究证实胃肠道也存在黑色素细胞,具备发生该瘤的组织学基础,故消化系统各个部位均可以发生~[3]。发生在食管、胃、小肠、肛门和直肠的黑色素瘤报道
Malignant Melanoma is a highly malignant tumor that originates from melanocytes in the neural crest. 90% of the primary malignant tumors originate in the skin and also occur in the mucous membranes, choroid, pia mater and eyes of the skin [1]. Primary in the digestive tract are rare, accounting for 1% to 3% of digestive tract malignancies [2], was considered to be metastatic, studies have confirmed that there are also melanoma cells in the gastrointestinal tract, with the occurrence of the histology of the tumor Basis, so all parts of the digestive system can occur ~ [3]. Occurs in the esophagus, stomach, small intestine, anus and rectum melanoma reported