论文部分内容阅读
目的：考察进口和国产尼莫地平注射剂与常用的输液液体配伍的稳定性。方法：利用分光光度法，测定进口和国产尼莫地平注射剂在５０ ｇ／Ｌ葡萄糖和ｆ９ ｇ／Ｌ氯化钠注射液液体中，于１８ ℃和３７ ℃避光和不避光条件下，不同时间段内吸光度变化。结果：不同条件下国产与进口尼莫地平注射剂与常用输液配伍后的吸光度变化程度基本一致，认为在ＮａＣｌ 溶液中６ ｈ 内是稳定的，而在葡萄糖溶液中２ ｈ 内稳定。结论：国产与进口尼莫地平与输液配伍后不同时刻点平均值之间差异无显著性
OBJECTIVE: To investigate the stability of compatibility between imported and domestic nimodipine injection and commonly used infusion fluids. Methods: The contents of imported and domestic nimodipine injection in 50 g / L glucose and f9 g / L sodium chloride injection liquid were determined by spectrophotometry at different temperatures of 18 ℃ and 37 ℃ Absorbance changes over time. Results: Under different conditions, the changes of absorbance of domestic and imported nimodipine injection and common infusion solution were basically the same, which were considered stable in 6 h in NaCl solution and stable in glucose solution within 2 h. Conclusion: There is no significant difference between the mean values of nimodipine at different time points