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目的了解恶性疟疾临床特征,早期识别重症患者和降低病死率。方法对2008年8月～2009年8月腾冲县人民医院经过血涂片检查确诊恶性疟疾192例患者的临床症状、诊治情况进行回顾性分析。结果各重症类型表现分别有意识障碍、重度贫血、循环衰竭、黄疸、水肿、心律失常及广泛出血等。192例重症恶性疟疾患者,痊愈185例(96.4%),留有后遗症2例(1.04%),死亡5例(3.6%)。结论尽早抗疟治疗,对抗药性及并发症的恰当处理是降低病死率的关键。氯喹有耐药趋势,青蒿琥酯是安全有效的首选药物。
Objective To understand the clinical features of falciparum malaria, identify critically ill patients early and reduce mortality. Methods The clinical symptoms, diagnosis and treatment of 192 cases of malignant malaria diagnosed by blood smear from August 2008 to August 2009 in Tengchong County People’s Hospital were analyzed retrospectively. Results The performance of various types of severe dysfunction, severe anemia, circulatory failure, jaundice, edema, arrhythmia and extensive bleeding. Of the 192 patients with severe malaria, 185 (96.4%) recovered, 2 (1.04%) left sequelae, and 5 deaths (3.6%). Conclusion As soon as possible, antimalarial treatment, drug resistance and complications of the appropriate treatment is the key to reducing mortality. Chloroquine resistant trend, artesunate is safe and effective drug of choice.