沙门氏菌属包括2千多种血清型。引起人类患病的有伤寒沙门氏菌、猪霍乱沙门氏菌、肠炎沙门氏菌和鼠伤寒沙门氏菌等。近年,伤寒沙门氏菌感染发病率高,且有耐药菌株的出现,鼠伤寒沙门氏菌感染的发病率逐年上升,病原治疗是近年临床上令人瞩目的问题,国内、外对此进行了大量临床研究,本文就其现状概述如下:一、伤寒沙门氏菌感染的病原治疗1.经典抗生素治疗现状:伤寒、副伤寒病原治疗经典使用的抗生素依次为氯霉素、复方新诺明、氨苄青霉素、呋喃唑酮和庆大霉素,①氯霉素:国内多数认为疗效显著,为首 Salmonella includes more than 2,000 serotypes. Salmonella typhi causing Salmonella typhi, Salmonella choleraesuis, Salmonella enteritidis and Salmonella typhimurium, which cause human diseases. In recent years, the incidence of Salmonella typhi infection is high, and the emergence of resistant strains, the incidence of Salmonella typhimurium infection increased year by year, pathogen treatment is clinically significant problem in recent years, a large number of clinical studies at home and abroad, The current status of this article are summarized as follows: First, the pathogen of Salmonella typhi infection treatment 1. The status of classic antibiotic treatment: typhoid, paratyphoid treatment of classic antibiotics used in turn were chloramphencolol, cotrimoxazole, ampicillin, furazolidone and celebrate Chloramphenicol, ① chloramphenicol: the majority of the domestic that the significant effect, led