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目的:探讨n 99Tcn m-人血清白蛋白(HSA) SPECT/CT显像对蛋白丢失性肠病的诊断价值。n 方法:回顾性分析2016年8月至2019年8月于郑州大学第一附属医院接受n 99Tcn m-HSA SPECT/CT检查的55例低蛋白血症患者[男21例，女34例，年龄5～78 (46.7±13.5)岁]的资料，以临床最终诊断为标准，分别计算动态平面显像和SPECT/CT显像对蛋白丢失性肠病的诊断效能，并采用n χ2检验对其进行统计学比较。n 结果:55例患者中46例临床最终诊断为蛋白丢失性肠病。n 99Tcn m-HSA平面显像和SPECT/CT显像对蛋白丢失性肠病诊断的灵敏度、特异性、准确性分别为91.30%(42/46)和100%(46/46)、6/9和8/9、87.27%(48/55)和98.18%(54/55)，组间差异均有统计学意义(n χ2值：5.73、4.27、5.42,均n P<0.05)。n 结论:在n 99Tcn m-HSA平面动态显像基础上，SPECT/CT显像对肠道蛋白丢失具有良好的诊断能力，对蛋白丢失性肠病具有较高的诊断效能。n “,”Objective:To investigate the diagnostic value of n 99Tcn m-human serum albumin (HSA) SPECT/CT imaging for protein-losing enteropathy.n Methods:Retrospective analysis was performed on 55 patients (21 males, 34 females, age: 5-78 (46.7±13.5) years) who had hypoproteinemia and underwent n 99Tcn m-HSA SPECT/CT imaging in the First Affiliated Hospital of Zhengzhou University between August 2016 and August 2019. The diagnostic efficiencies of dynamic planar imaging and SPECT/CT imaging for protein-losing enteropathy were evaluated according to the clinical final diagnosis. n χ2 test was used for data analysis.n Results:The final clinical diagnosis confirmed 46/52 patients were with protein-losing enteropathy. The sensitivities, specificities and accuracies of n 99Tcn m-HSA planar imaging and SPECT/CT imaging for the diagnosis of protein-losing enteropathy were 91.30% (42/46) n vs 100% (46/46), 6/9 n vs 8/9, and 87.27% (48/55) n vs 98.18%(54/55), respectively. The differences in sensitivity, specificity and accuracy were all statistically significant (n χ2 values: 5.73, 4.27, 5.42, all n P<0.05).n Conclusion:Based on n 99Tcn m-HSA planar dynamic imaging, SPECT/CT imaging has good diagnostic ability for intestinal protein loss and high diagnostic efficiency for protein-losing enteropathy.n