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目的:分析降糖增敏汤联合二甲双胍治疗老年2型糖尿病胰岛素抵抗的临床疗效。方法:以2014年6月-2016年5月间收治的66例老年2型糖尿病胰岛素抵抗患者为研究对象,随机分为两组,每组33例,对照组采取二甲双胍治疗,观察组联用降糖增敏汤治疗,对比两组疗效。结果:观察组临床总有效率明显高于对照组(P<0.05);治疗后观察组的空腹血糖、餐后2h血糖、空腹胰岛素(FINS)、胰岛素抵抗指数(IRI)及胰岛素敏感指数(ISI)水平均明显优于对照组(P<0.05)。结论:使用降糖增敏汤联合二甲双胍治疗老年2型糖尿病胰岛素抵抗效果理想,有利于改善预后。
Objective: To analyze the clinical efficacy of Jiangshenzengmin Decoction combined with metformin in the treatment of insulin resistance in type 2 diabetic elderly patients. Methods: Sixty-six elderly patients with type 2 diabetes mellitus with insulin resistance admitted from June 2014 to May 2016 were randomly divided into two groups (n = 33 in each group). The control group was treated with metformin, Sugar-sensitive soup treatment, the two groups compared efficacy. Results: The total effective rate in observation group was significantly higher than that in control group (P <0.05). After treatment, the fasting blood glucose, postprandial 2h blood glucose, fasting insulin (FINS), insulin resistance index (IRI) and insulin sensitivity index ) Levels were significantly better than the control group (P <0.05). Conclusion: It is effective to use hypoglycemic Zengmin Decoction combined with metformin to treat type 2 diabetes mellitus in elderly patients with insulin resistance and to improve prognosis.