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目的对肛管、直肠癌进行综合治疗,并对其预后因素加以分析。方法选择哈医大附属肿瘤医院1978～2005年收治的96例肛管癌患者进行回顾性分析,TNM分期:T13例,T231例,T337例,T425例,均经病理证实,给予手术、放疗、化疗等综合治疗。采用SAS软件进行统计分析,对资料进行单因素及多因素COX回归分析。结果直肠、肛管癌1年、3年、5年生存率分别为:86.45%,39.58%,19.79%,中位生存时间36.72个月。结论肛门指诊是发现和诊断肛管癌的重要手段,放疗及手术、化疗等综合治疗是直肠、肛管癌的主要治疗方法,肿瘤分期、腹股沟淋巴结转移、治疗方法以及肿瘤分化是影响预后的主要因素。
Objective To treat the anal canal and rectum cancer comprehensively and analyze its prognostic factors. Methods Ninety-six patients with anal cancer who were admitted to Affiliated Oncology Hospital of Harbin Medical University from 1978 to 2005 were retrospectively analyzed. The TNM staging was T13, T231, T337 and T425, all of which were confirmed by pathology. The patients underwent surgery, radiotherapy and chemotherapy Comprehensive treatment. Using SAS software for statistical analysis, the data were single factor and multivariate COX regression analysis. Results The 1-year, 3-year and 5-year survival rates of rectal and anal cancer were 86.45%, 39.58% and 19.79%, respectively. The median survival time was 36.72 months. Conclusion Anus refers to the diagnosis and treatment of anal cancer is an important means of radiotherapy and surgery, chemotherapy and other comprehensive treatment of rectal and anal cancer is the main treatment, tumor staging, inguinal lymph node metastasis, treatment and tumor differentiation is prognostic major factor.