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临床上,不少非甲状腺疾病(non-thyroidal illness,NTI)病人的甲状腺激素检查异常,统称为“正常甲状腺病态综合,征”(euthyroid sick syndrome),其机理未完全阐明。但是,它与甲状腺疾病的鉴别诊断、治疗和预后直接有关。本文就NTI病人甲状腺激素的异常及其与预后的关系作一概述。 NTI甲状腺功能异常的类型 NTI病人甲状腺功能异常包括:①低三碘甲状腺原氨酸(T_3)综合征;②低T_3、甲状腺素(T_4)综合征;③高T_4综合征;④混合型。低T_3综合征为选择性的T_3缺乏症。指临床上甲状腺
Clinically, many patients with non-thyroidal disease (NTI) thyroid hormone abnormalities, collectively referred to as “normal thyroid disease syndrome,” (euthyroid sick syndrome), the mechanism is not fully elucidated. However, it is directly related to the differential diagnosis, treatment and prognosis of thyroid diseases. This article gives an overview of the abnormality of thyroid hormone in patients with NTI and its relationship with prognosis. Types of NTI Thyroid dysfunction Thyroid dysfunction in patients with NTI include: ① low triiodothyronine (T_3) syndrome; ② low T_3, thyroid hormone (T_4) syndrome; ③ high T_4 syndrome; ④ mixed type. Low T 3 syndrome is a selective T_3 deficiency. Refers to the clinical thyroid