弥散性血管内凝血(DIC)是指在某些致病因素的作用下,微循环中发生广泛的微血栓,后者由血小板聚集和纤维蛋白沉积而成,由此引起以下病变:①消耗大量凝血因子引起严重出血倾向;②多发性微血栓导致器官、组织的缺血坏死;③继发纤维蛋白溶解加重出血。多数DIC病例病情严重,发展迅速,如不及时救治常危及生命。 DIC可发生在许多疾病的过程中,如各种感染性疾病、组织损伤(包括手术)、肿瘤、产科意外等。休克与DIC关系密切。二者可互为因果,已知休克可诱发DIC,而DIC亦可引起或加重休克,二者往往可由同一因素引起(如感染),在病理变化上相互联系,仅临床表现不同而已。 Disseminated intravascular coagulation (DIC) refers to the role of some of the risk factors, microcirculation occurs in a wide range of micro-thrombosis, the latter by the platelet aggregation and fibrin deposition, resulting in the following lesions: ① consume a large amount Coagulation factors cause severe bleeding tendency; ② multiple microthrombus leading to organ and tissue ischemia and necrosis; ③ secondary fibrinolysis aggravate bleeding. The majority of DIC cases are in serious condition with rapid development. If not timely treatment is often life-threatening. DIC can occur in many diseases, such as various infectious diseases, tissue damage (including surgery), cancer, obstetrics and so on. Shock and DIC are closely related. The two can each cause and effect, known shock can induce DIC, and DIC can also cause or aggravate shock, both often caused by the same factor (such as infection), pathological changes in the interconnected, only clinical manifestations are different.