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目的剖析肺表面活性物质在新生儿急性呼吸窘迫综合征中的应用价值。方法收集2015年10月~2016年12月我科收录的46例急性呼吸窘迫综合征患儿,并将之按照奇偶数字分组的方式分成甲、乙两组(n=23)。两组都接受机械通气治疗,甲组同时加用肺表面活性物质。分析比较两组的治疗效果。结果甲组的呼吸机使用时间为(103.26±24.81)h、症状恢复时间为(3.11±1.26)h,均明显短于乙组的(143.37±17.89)h、(4.98±1.74)h,P<0.05。甲组并发症发生率为8.7%,明显低于乙组,P<0.05。甲组疗效总有效率为95.65%,乙组为78.26%。甲组明显高于乙组,P<0.05。结论新生儿急性呼吸窘迫综合征用肺表面活性物质,效果好,临床症状缓解速度快,并发症少,可供借鉴。
Objective To analyze the value of pulmonary surfactant in neonatal acute respiratory distress syndrome. Methods Forty-six children with acute respiratory distress syndrome were enrolled in our department from October 2015 to December 2016. They were divided into groups A and B according to parity numbers (n = 23). Both groups were treated with mechanical ventilation, a group also added pulmonary surfactant. Analysis and comparison of the two groups of treatment. Results The duration of ventilator recovery in group A was (103.26 ± 24.81) h and the recovery time was (3.11 ± 1.26) h in group A, which was significantly shorter than that in group B (143.37 ± 17.89) h and (4.98 ± 1.74) h, P < 0.05. The incidence of complications in group A was 8.7%, significantly lower than that in group B (P <0.05). Group A total effective rate was 95.65%, B was 78.26%. Group A was significantly higher than group B, P <0.05. Conclusions Pulmonary surfactant in neonatal acute respiratory distress syndrome has good effect, quick response to clinical symptoms and few complications.