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本文应用自制的稳定性粗颗粒抗癌复合性乳剂(亦称复乳)行肝动脉化疗栓塞术治疗32例肝癌,对其疗效进行了详细探讨。并与47例应用碘油与抗癌药直接混合治疗的病人的结果进行了比较分析。结果显示:肿瘤缩小率大于50%者,治疗组及对照组病人分别占84.4%及61.7%,统计结果表明有显著差异(P>0.05)。6、12、18个月生存率,治疗组及对照组分别为100%、96.3%、81.0%,93.6%、76.2%、54.1%,统计结果显示12及18个月生存率,两组病人有显著差异(P<0.05)。治疗组病人的毒副反应及合并症明显低于对照组,无严重合并症发生,对症治疗后短期内恢复正常。我们制做的抗癌药复合性乳剂稳定性好、用于肝动脉内化疗栓塞治疗肝癌效果好、毒性低.
In this paper, 32 cases of liver cancer were treated with self-made stable coarse-particle anticancer compound emulsion (also known as double emulsion) for transcatheter arterial chemoembolization. The curative effect was discussed in detail. The results of 47 patients treated with lipiodol and anticancer drugs were directly compared and analyzed. The results showed that: tumor shrinkage rate is greater than 50%, treatment group and control group patients accounted for 84.4% and 61.7%, respectively, statistical results show that there are significant differences (P> 0.05). The survival rates at 6, 12, and 18 months were 100%, 96.3%, 81.0%, 93.6%, 76.2%, and 54.1% in the treatment and control groups, respectively. The statistical results showed 12- and 18-month survival rates. There were two groups of patients. Significant difference (P<0.05). The toxic and side effects and complications of the patients in the treatment group were significantly lower than those in the control group. No serious complications occurred and the symptoms returned to normal in the short term after symptomatic treatment. Our compound anti-cancer drug emulsions have good stability and are effective for hepatocellular carcinoma in hepatic arterial chemoembolization and have low toxicity.