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本文报道了McAb(4F_2)ELISA检测囊尾蚴循环抗原诊断脑囊虫病试剂盒的研制。实验对227例脑囊虫病患者脑脊液进行检测,循环抗原阳性率为84.58％,其中活动型脑囊虫病患者171例,循环抗原阳性率为93.57％。56例非活动型脑囊虫病患者,循环抗原阳性率为57.14％,前者的循环抗原强度也明显高于后者。83例患有其它中枢神经系统疾病的患者,1例阳性,阴性符合率为98.80％。本试验方法简便,结果客观,对脑囊虫病特别是活动型脑囊虫病敏感性高、特异性强。
This article reports the McAb (4F_2) ELISA detection cysticercosis circulating antigen diagnosis of cerebral cysticercosis kit development. Cerebrospinal fluid was detected in 227 patients with cysticercosis, the positive rate of circulating antigen was 84.58%, of which 171 cases were active cysticercosis, the positive rate of circulating antigen was 93.57%. In 56 patients with inactive brain cysticercosis, the positive rate of circulating antigen was 57.14%, and the former had a significantly higher circulating antigen intensity than the latter. In 83 patients with other central nervous system diseases, one was positive and the other was negative. The coincidence rate was 98.80%. The test method is simple, objective and objective, positive for cysticercosis, especially active cysticercosis, high specificity and specificity.