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目的:研究急性等容血液稀释(ANH)在肿瘤手术中的应用。方法:对30例食管或贲门癌病人行ANH,比较血液稀释前后血流动力学和血常规变化。结果:86．7％病人围手术期未输库血:血液稀释前、后30min以及自血回输后,心率、平均动脉压和血氧饱和度无显著性差异;稀释后30min与稀释前相比,血红蛋白、红细胞压积和红细胞显著减少(P< 0．05),但自血回输后无显著性差异,ANH对血小板无明显影响。结论:ANH可有效减少肿瘤痛人手术中输入库血。
Objective: To study the application of acute isovolemic hemodilution (ANH) in tumor surgery. Methods: Thirty patients with esophageal or cardiac cancer underwent ANH. The hemodynamics and blood routine before and after hemodilution were compared. Results: There was no significant difference in heart rate, mean arterial pressure and oxygen saturation between 86.7% patients before perioperative blood transfusion and 30 min before and after transfusion, Hemoglobin, hematocrit and erythrocytes were significantly decreased (P <0.05), but there was no significant difference after self-blood transfusion. ANH had no significant effect on platelets. Conclusion: ANH can effectively reduce the input of blood bank in patients with tumor pain.