作者用单剂量给予布洛芬、佐美酸钠、阿司匹林和安慰剂口服的方法,治疗外阴切开的术后剧痛,以比较几种药物的镇痛作用。120名受试者,按照双盲法,平行分组,比较试验时间为4小时,剂量为400mg布洛芬、100mg佐美酸钠、600mg阿司匹林。从大多数参数(包括疼痛强度差异总数和每小时疼痛减低值总数在内)看来,几种药物存在着差异,但均比安慰剂有效,而布洛芬又比阿司匹林和佐美酸钠有效,400mg布洛芬的效力超过100mg佐美酸钠或600mg阿司药学通报1984年第19卷第7期 The authors used a single dose of ibuprofen, sodium silylate, aspirin and placebo oral treatment of genital incision pain after surgery to compare the analgesic effect of several drugs. 120 subjects were grouped in parallel according to a double-blind method, with a comparative trial duration of 4 hours, a dose of 400 mg of ibuprofen, 100 mg of sodium sodialate, and 600 mg of aspirin. Several drugs differed from most parameters (including the total number of pain intensity differences and the total number of pain reductions per hour), but both were more effective than placebo, with ibuprofen being more effective than aspirin and sodium sodialate, 400mg ibuprofen effectiveness of more than 100mg sodium acid or 600mg Aspir Pharmacy Bulletin 1984 Volume 19 No. 7