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本文报告了小剂量α-干扰素配伍聚肌胞治疗慢性乙型活动性肝炎的效果。将在我院1986-1988年住院的40例乙型慢活肝患者,随机分为试验组与对照组各20例。试验组应用小剂量α-干扰素加聚肌胞,对照组仅用对症及支持疗法。经三个月观察:试验组总有效率为75％,对照组仅为25％。两组有显著差异;P<0.01。在HBsAg及HBeAg的系统转换上,试验组办较对照组为优,有显著差异。
This article reports the effect of low-dose alpha-interferon in combination with polymyosal in the treatment of chronic hepatitis B activity. Forty B patients with chronic liver disease who were hospitalized from 1986 to 1988 in our hospital were randomly divided into experimental group and control group with 20 cases each. The experimental group applied a small dose of α-interferon plus poly-muscle cells, the control group only symptomatic and supportive therapy. After three months of observation, the total effective rate was 75% in the experimental group and only 25% in the control group. There was a significant difference between the two groups; P <0.01. In the system conversion of HBsAg and HBeAg, the experimental group was superior to the control group, with significant differences.