论文部分内容阅读
目的探讨冬凌草液膀胱腔内热疗对膀胱癌患者细胞免疫功能的影响。方法对28例膀胱癌患者术后行冬凌草液膀胱腔内热疗,分别采用免疫荧光法和ELISA法检测治疗前后外周血T淋巴细胞亚群和血清SIL-2R水平的变化,并与健康对照组进行比较分析。结果膀胱癌患者细胞免疫功能低下,表现为CD4+T、CD4+/CD8+低于正常人,而CD8+T、SIL-2R高于正常人,且术后无明显改变。经冬凌草液热疗后,CD4+T、CD4+/CD8+则升高,SIL-2R降低。结论冬凌草液膀胱腔内热疗可以提高膀胱癌患者的免疫功能。
Objective To investigate the effect of Rubescens Bladder fluid in bladder cavity on the cellular immune function in patients with bladder cancer. Methods Twenty-eight patients with bladder cancer underwent intravesical intravitreal hyperthermia. The changes of T lymphocyte subsets and serum SIL-2R levels in peripheral blood before and after treatment were detected by immunofluorescence and ELISA respectively. Control group for comparative analysis. Results The immune function of bladder cancer patients was low, showing CD4 + T, CD4 + / CD8 + lower than that of normal people, while CD8 + T and SIL-2R were higher than those of normal people. Rubescens thermotherapy, CD4 + T, CD4 + / CD8 + is increased, SIL-2R decreased. Conclusion Rubescens fluid intravesical hyperthermia can improve the immune function of bladder cancer patients.