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目的:探讨血清抗幽门螺杆菌(HP)抗体IgG滴度与十二指肠球部溃疡(DU)的关系。方法:54例DU患者与54例慢性胃炎患者均经胃镜确诊,活检HP尿素酶检测,并应用ELISA法测定血清抗HP抗体IgG滴度。结果:球溃疡组活检HP检出率81.48％,慢性胃炎组HP检出率为83.33％,统计学处理差异无显著性(P>0.05);球溃疡组的血清抗HP抗体IgG滴度与慢性胃炎组比较差异显著(P<0.01)。结论:血清抗HP抗体IgG滴度明显升高者(>3000)以球溃疡者显著多于慢性胃炎者,提示血清抗HP抗体IgG显著增高者(>3000)即使胃镜检查未发现病变者可能仍需抗HP治疗。
Objective: To investigate the relationship between serum anti-Helicobacter pylori (HP) antibody IgG titer and duodenal ulcer (DU). Methods: 54 cases of DU patients and 54 cases of chronic gastritis were diagnosed by gastroscopy, biopsy and urease test, and serum anti-HP IgG antibody titer was measured by ELISA. Results: The detection rate of HP in ball ulcer group was 81.48%, the detection rate of HP in chronic gastritis group was 83.33%, there was no significant difference between the two groups (P> 0.05) Gastritis group was significantly different (P <0.01). Conclusion: Serum anti-HP IgG antibody titer was significantly higher (> 3000), those with ball ulcer were significantly more than those with chronic gastritis, suggesting a significant increase in serum anti-HP IgG antibody (> 3000) even if gastroscopy was not found lesions may still Anti-HP treatment required.