目的 本次试验将采用益气养阴通络法对糖尿病肾脏病(DKD)患者实施治疗，分析其作用机制?方法 试验选取了2018年8月至2019年7月确诊为糖尿病肾脏病的患者作为研究对象?通过回顾式分析，在征得患者同意的基础上，对数据信息进行搜寻，并开展随机分组调查?参与患者共计78例，在分组上为随机分组，以公平性为开展前提?对照组(n=39)患者采用基础措施，观察组(n=39)应用益气养阴通络法+ 基础治疗，分析治疗疗效的差异?结果 从治疗结局上看，观察组(n=39)患者在血肌酐?尿素氮水平上有明显下降，分别为(80.“,”Objective In this experiment，the patients with diabetic kidney disease (DKD) will be treated by supplementing qi，nourishing yin and dredging collaterals，and its mechanism will be analyzed.Methods The patients diagnosed with diabetic kidney disease from August 2018 to July 2019 were selected as our research objects.Through retrospective analysis，on the basis of obtaining patients\' consent，the data information was searched，and random grouping investigation was carried out.A total of 78 patients participated in the study，which were randomly divided into groups with fairness as the prerequisite.Patients in the control group (n=39) were treated with basic measures，while those in the observation group (n=39) were treated with the method of invigorating qi，nourishing yin and dredging collaterals plus basic treatment to analyze the curative effect of Chile\'s pride.Results From the treatment outcome，the levels of serum creatinine and urea nitrogen in the observation group decreased signi?cantly，which were (80.30±8.70) mmol/L and (3.50±0.70) mmol/L，while those in the control group were (105.60±10.60) mmol/L and (6.20±1.30) mmol/L.Meanwhile，the level of α-klotho protein in the observation group was (1 307.90±2 011.60) pg/mL，which was higher than that in the control group (836.80±120.30) pg/mL，and the difference was statistically signi?cant.Conclusion The method of invigorating qi，nourishing yin and dredging collaterals is helpful to improve the condition of patients with diabetic kidney disease，and can regulate the relationship with α-klotho protein level.It has good clinical application effect and can be popularized.