论文部分内容阅读
目的 :研究腹腔镜根治性切除术联合新辅助放化疗治疗中低位直肠癌的可行性和安全性。方法 :收集2012年5月至2015年5月80例新辅助放化疗后的中低位直肠癌病人,非随机分为腹腔镜组(n=42)和开腹组(n=38)。比较两组病人的手术相关指标、术后恢复情况及并发症。结果 :两组病人在保肛率和预防性肠造口率均无统计学差异。腹腔镜组手术时间显著长于开腹组,术后肠功能恢复显著早于开腹组,两组术中出血量、术后并发症发生率和术后住院时间无统计学差异。两组清扫淋巴结总数及远切端长度无统计学差异。两组环周切像均阴性。结论:中低位直肠癌新辅助放化疗后行腹腔镜手术安全。
Objective: To study the feasibility and safety of laparoscopic radical resection and neoadjuvant chemoradiotherapy in the treatment of low and middle rectal cancer. Methods: From May 2012 to May 2015, 80 patients with low and middle rectal cancer after neoadjuvant chemoradiation were randomly divided into laparoscopic group (n = 42) and open group (n = 38). The operation-related indexes, postoperative recovery and complications of the two groups were compared. Results: There was no significant difference between the two groups in the rate of anus retention and prophylactic intestinal metaostomy. The operation time of laparoscopic group was significantly longer than that of laparotomy group. The recovery of intestinal function after operation was significantly earlier than that of laparotomy group. There was no significant difference between the two groups in intraoperative blood loss, postoperative complication rate and length of postoperative hospital stay. There was no significant difference between the two groups in terms of total lymph node dissection and distal incision length. The two groups of circumcision were negative. Conclusion: Laparoscopic surgery is safe after neoadjuvant radiochemotherapy in low or middle rectal cancer.