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祛痰宁005~04g/kgig及01~025g/kgsc给药有增强大小鼠气管排泌酚红的作用,其作用随剂量的增加而增强;02~08g/kg能加强毛果芸香碱引起的小鼠流涎作用,作用随着剂量的增加而增强,04g/kg与必嗽平的作用相当;祛痰宁油010~040g/kgig1h后能显著抑制鸡蛋清引起的足肿胀,其抑制作用随着剂量的增加而增强;03g/kgig及005g/kgip时对巴豆油致炎引起的鼠耳肿胀有明显的抑制作用;010g/kgig给药时对氨水刺激引起的咳嗽有止咳作用,040g/kg的止咳作用与可待因006g/kg相当。实验结果表明祛痰宁的毒副作用小,治疗范围宽。
The effects of Suining 005~04g/kgig and 01~025g/kgsc enhance the effect of tracheal excretion of phenol red in rats, and its effect increased with the increase of dose; 02~0 8g/kg can enhance the purgative effect of pilocarpine on mice, and the effect increases with the increase of dose. The effect of 04g/kg is equivalent to that of bismuthine. After the sulphur dioxide oil is 010~040g/kgig1h, Can significantly inhibit the swelling of the feet caused by egg white, and its inhibitory effect increases with the dose; 0 3g/kgig and 0 05g/kgip has a significant inhibitory effect on ear swelling caused by croton oil inflammation; 0 When 10 g/kgig was administered, there was cough suppressing effect on cough caused by ammonia stimulation. The antitussive effect of 040 g/kg was equivalent to 006 g/kg codeine. The experimental results show that Funing has a small toxic side effect and a wide therapeutic range.