用CA15I－3RIA测定了41例术前乳腺肿瘤和113例乳腺癌术后患者的血清。其中，术前25例为乳腺癌，其灵敏度为20．0％，特异性为93．7％；59例诊断为乳腺癌术后复发者，灵敏度为71．2％。50例诊断为骨转移者，灵敏度为78．0％．结果表明：由于CA15－3对早期乳腺癌的灵敏度较低，不适于作乳腺癌普查。但是，它对于乳腺癌术后复发、转移，尤其是对骨等脏器的转移具有较高的诊断价值。 The sera of 41 patients with preoperative breast tumors and 113 patients with postoperative breast cancer were measured with CA15I-3 RIA. Among them, 25 patients were breast cancer before surgery, the sensitivity was 20.0%, and the specificity was 93.7%; 59 patients were diagnosed as breast cancer patients with recurrence, and the sensitivity was 71.2%. Of the 50 patients diagnosed with bone metastases, the sensitivity was 78.0%. The results show that CA15-3 is not suitable for breast cancer screening due to its low sensitivity to early breast cancer. However, it has a high diagnostic value for the recurrence and metastasis of breast cancer, especially for the transfer of bone and other organs.