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目的:研究分析调强或三维适形放疗联合TP方案化疗治疗局部中晚期食管癌的效果。方法:选取我院收治的60例局部中晚期食管癌的患者,随机分为对照组和观察组,每组各30例。其中对照组予以调强联合TP方案化疗,观察组则予以三维适形放疗联合TP方案化疗,对比两组患者的治疗效果。结果:对照组患者有效有26例(86.67%),观察组患者治疗有效为25例(83.33%),两组间无显著性差异(P>0.05),无统计学意义。对照组中第1年患者生存有25例(83.33%),第2年生存有20例(66.67%),第3年患者生存有17例(56.67%);观察组中第1年患者生存有26例(86.67%),第2年生存有19例(63.33%),第3年患者生存有15例(50.0%)。两组间无显著性差异(P>0.05),无统计学意义。结论:调强或三维适形放疗联合TP方案化疗治疗均可明显改善患者症状,两者间治疗效果基本相等,可根据患者实际情况予以治疗措施,来有效提高患者的生存质量等。
Objective: To study the effect of intensity modulated or three-dimensional conformal radiotherapy combined with TP regimen in the treatment of locally advanced esophageal cancer. Methods: Sixty patients with locally advanced esophageal cancer who were admitted to our hospital were randomly divided into control group and observation group, with 30 cases in each group. The control group was combined with TP regimen chemotherapy, and the observation group was treated with three-dimensional conformal radiotherapy combined with TP regimen to compare the therapeutic effect of the two groups. Results: There were 26 cases (86.67%) in the control group and 25 cases (83.33%) in the observation group. There was no significant difference between the two groups (P> 0.05). There was no statistical significance. In the control group, there were 25 cases (83.33%) in the first year, 20 cases (66.67%) in the second year and 17 cases (56.67%) in the third year. The survival of the first year in the observation group was There were 26 cases (86.67%), 19 cases (63.33%) in the second year and 15 cases (50.0%) in the third year. No significant difference between the two groups (P> 0.05), no statistical significance. CONCLUSION: IMRT or TPT combined chemotherapy can significantly improve the symptoms of patients. The treatment effect between them is basically the same, which can be treated according to the actual situation of the patients so as to effectively improve the quality of life of the patients.