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目的探讨匹多莫德辅助治疗儿童毛细支气管炎的临床疗效。方法收集2009年2月-2010年4月儿科门诊及病房符合毛细支气管炎诊断的患儿50例,随机分为治疗组与对照组各25例。对照组采用布地奈德,沙丁胺醇交替雾化,采用抗病毒药物,根据感染情况添加抗生素,并给予激素静脉滴注。治疗组在对照组基础上加用匹多莫德片。比较2组患儿治疗后的临床疗效。结果对照组总有效率为72.0%,治疗组总有效率为84.0%,治疗组患儿治疗后疗程较对照组缩短,差异有统计学意义(P<0.05)。治疗期间未见明显不良反应,患儿依从性100.0%。结论匹多莫德用于儿童反复呼吸道感染临床急性期治疗、缓解期预防均有明显疗效,且无明显不良反应,为口服剂型,使用方便,减轻了患儿的痛苦,并减少了在院时间,值得推广。
Objective To investigate the clinical efficacy of pidotimod in children with bronchiolitis. Methods Fifty children with pediatric bronchitis and bronchiolitis diagnosed from pediatric clinic and ward were collected from February 2009 to April 2010 and randomly divided into treatment group (25 cases) and control group (25 cases). Control group budesonide, albuterol alternately atomization, the use of antiviral drugs, antibiotics added according to the infection, and given hormone intravenous drip. The treatment group was added Pidotimod tablets on the basis of the control group. The clinical effects of two groups were compared. Results The total effective rate of the control group was 72.0%, the total effective rate of the treatment group was 84.0%. The treatment course of the treatment group was shorter than that of the control group after treatment, the difference was statistically significant (P <0.05). No significant adverse reactions during treatment, compliance in children 100.0%. Conclusion Pidotimod was used in the acute phase of children with recurrent respiratory tract infections. The effective rate of prophylaxis in remission period was no significant adverse reactions. It was an oral dosage form, easy to use, alleviated the pain of children and reduced the time spent in hospital , Worth promoting.