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目的异丙酚复合小剂量芬太尼在胃镜检查中的应用,观察其镇痛效果和对呼吸、循环及清醒质量的影响。方法选择ASAI～Ⅱ级门诊或住院胃镜检查病人260例,应用异丙酚复合小剂量芬太尼实施无痛胃镜,观察患者在麻醉前、麻醉中及麻醉后平均动脉压、心率、动脉血氧饱和度的变化及苏醒时间、定向力恢复时间。结果各项指标与检查前比较无显著性差异,患者苏醒时间(2.31±0.67)min,定向力恢复时间(10.2±1.80)。结论小剂量芬太尼加强镇痛,减轻镇静深度和伤害性反应,减少异丙酚的用药量,又不影响清醒质量,不失为一种更加安全有效的麻醉方法。
Objective To investigate the application of propofol combined with fentanyl in gastroscopy to observe its analgesic effect and its effects on respiration, circulation and sober quality. Methods A total of 260 patients with ASAI Ⅱ level outpatient or inpatient gastroscopy were enrolled in this study. Propofol combined with small dose of fentanyl was administered to patients with painless gastroscopy. Before anesthesia, anesthesia and mean arterial pressure, heart rate, arterial oxygenation Saturation changes and wake-up time, recovery time of directional force. Results There was no significant difference between each index and before examination. The recovery time was (2.31 ± 0.67) min and the recovery time was 10.2 ± 1.80. Conclusions Small dose of fentanyl can enhance analgesia, reduce the depth of sedation and nociceptive response, reduce the dosage of propofol, and do not affect the quality of soberness, after all, it is a safer and more effective method of anesthesia.