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幽门螺杆菌(Hp)是寄生在胃粘膜上皮上的螺旋状短杆菌,1983年由澳大利亚的 Warren 等分离出。Hp 与胃炎、消化性溃疡有关,受到瞩目。最近,它作为胃癌的致病因子之一也正在探讨之中。1984年日本井上等分离培养成功,但感染途径和感染方式等尚不清楚。经内镜检查确诊的消化性溃疡和胃炎的患者,Hp感染率比健康人高,Hp 在胃粘膜上皮最易发生的部位,组织学上伴有中性粒细胞浸润,即所谓慢性活动性胃炎。此外,合并有 Hp 感染的消化性溃疡患者,也治愈迁延,在溃疡的治疗过程中,试行去除 Hp,则可
Helicobacter pylori (Hp) is a parasitic on the gastric mucosa of Helicobacter species, separated by Warren in Australia in 1983. Hp and gastritis, peptic ulcer, attracted attention. Recently, it is also being explored as a causative agent of gastric cancer. In 1984, Japan’s Inoue Isoetry was successfully cultivated, but the route of infection and the way of infection were not yet known. Patients diagnosed by endoscopy for peptic ulcer and gastritis, Hp infection rate higher than healthy people, Hp in gastric mucosal epithelium most prone to site, histologically associated with neutrophil infiltration, the so-called chronic active gastritis . In addition, patients with peptic ulcer complicated by Hp infection also have a prolonged cure. Hp can be removed on a trial basis during the course of ulcer treatment