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目的:探讨分析多药治疗糖尿病过程中全程化药学干预效果。方法:回顾性分析笔者所在医院2012年7月-2013年8月收治的100例糖尿病患者的临床资料,并按照随机数字表法将其分为对照组和观察组,每组50例。对照组在多药治疗的过程中采取常规治疗方法,而观察组在进行多药治疗期间采用药学干预方法,观察比较两组患者的用药依从性、满意度、药物不良事件发生情况及用药偏差等。结果:经治疗后,观察组的用药依从性提高幅度明显高于对照组,差异有统计学意义(P<0.05)。两组患者的全部药物不良事件发生率比较差异均无统计学意义(P>0.05)。观察组的患者满意度98.0%明显高于对照组的80.0%,且一般医疗过程和药物指导非常满意率均明显高于对照组,用药偏差率明显低于对照组,差异均有统计学意义(P<0.05)。结论:在糖尿病多药治疗中采取药学干预可提高患者用药依从性和满意度,并降低用药偏差,药师的干预不仅能够规范医师临床用药行为,同时也可改善临床不合理用药情况,进而保证医疗卫生中的安全用药,但是对于药物不良事件发生率的控制无显著差异。
Objective: To investigate the effect of full-time pharmacy intervention in the treatment of diabetes mellitus with multi-drug. Methods: The clinical data of 100 diabetic patients admitted to our hospital from July 2012 to August 2013 were retrospectively analyzed. According to the random number table, they were divided into control group and observation group, 50 cases in each group. The control group took conventional treatment in the course of multi-drug therapy, while the observation group used the method of pharmacy intervention during the multi-drug treatment, and observed and compared the drug compliance, satisfaction, adverse drug events and medication deviation in the two groups . Results: After treatment, the observation group’s medication compliance was significantly higher than the control group, the difference was statistically significant (P <0.05). There was no significant difference between the two groups in the incidence of all the adverse drug reactions (P> 0.05). The satisfaction rate of patients in the observation group was significantly higher than that of the control group (98.0%, 80.0%), and the general satisfaction rate of medical procedure and drug guidance was significantly higher than that of the control group (P <0.05). The deviation rate of the medication was significantly lower than that of the control group P <0.05). Conclusion: Pharmacological intervention in multi-drug treatment of diabetes can improve compliance and satisfaction of drug users and reduce medication deviation. Pharmacist intervention can not only regulate the clinical medication behavior of physicians, but also improve the clinical irrational drug use, and then ensure that medical treatment Health in the safe medication, but for the incidence of adverse drug events control no significant difference.