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本文应用单克隆抗体酶免疫法检测了206例各种病人血清和胃液中癌胚抗原(CEA)的含量,胃癌患者血清和胃液CEA含量均明显高于正常人及良性胃病患者.非胃癌的其它恶性肿瘤患者胃液CEA含量无增高现象。这些结果表明检测胃液CEA含量可用于胃癌的辅助诊断、疗效评价、术后监测和胃癌高危人群的筛选。在胃癌患者中血清CEA阳性率低于胃液,故同时检测血清与胃液CEA可提高胃癌诊断的阳性率.对指导治疗和估计预后也有帮助。
In this study, the levels of carcinoembryonic antigen (CEA) in serum and gastric fluid of 206 patients were detected by monoclonal antibody enzyme immunoassay. The CEA levels in serum and gastric juice of gastric cancer patients were significantly higher than those of normal and benign gastropathy patients. There was no increase in CEA content in gastric juice in patients with malignant tumors. These results show that the detection of CEA content in gastric juice can be used for the diagnosis of gastric cancer, evaluation of therapeutic effect, postoperative monitoring and screening of high-risk groups for gastric cancer. In patients with gastric cancer, the positive rate of serum CEA is lower than that of gastric juice. Therefore, simultaneous detection of CEA in serum and gastric juice can increase the positive rate of diagnosis of gastric cancer. It also helps to guide treatment and estimate prognosis.