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阿斯匹林(乙酰水杨酸ASA)是经典的解热镇痛药。由于其具有抑制前列腺素(PG)合成及干预血小板机能的作用,近年来被日趋广泛地用作为抗血栓治疗剂,尤其是在心血管系统方面。 ASA对抗血栓形成的机理 ASA通过灭活脂肪酸环氧化酶而抑制前列腺环素(PGI_2)的生成及循环血中血小板的机能。目前已知当血管内发生血小板
Aspirin (acetylsalicylic acid ASA) is a classic antipyretic analgesic. In recent years it has been increasingly used as an antithrombotic agent, especially in the cardiovascular system, due to its inhibitory effect on prostaglandin (PG) synthesis and its ability to interfere with platelet function. Mechanism of ASA against thrombosis ASA inhibits the production of prostacyclin (PGI_2) and the function of circulating platelets in blood by inactivating fatty acid cyclooxygenase. It is currently known that intravascular platelets occur