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肺巨噬细胞(PM,下同)在防止微生物感染和清除吸入肺内异物等方面起着重要作用,但肺与外界直接交通,某些环境和人为因素均可影响其功能,这为肺部某些疾病的发生创造了条件。另一方面,PM在其机能活动中,释放的某些毒性物质和弹力蛋白酶等,也可能造成肺损伤。因此探讨外界因素对PM的影响为进一步弄清PM与肺部疾病的关系,阐明某些肺部疾病的发病机理及其防治具有重要意义。肺泡巨噬细胞(AM,下同)是PM的重要组成
Pulmonary macrophages (PM, the same below) play an important role in preventing microbial infections and removing foreign bodies in the lungs, but direct transport of the lungs to the outside world and certain environmental and anthropogenic factors can affect their function as pulmonary Some diseases have created the conditions. On the other hand, some toxic substances and elastase released by PM during its functional activities may also cause lung injury. Therefore, to explore the impact of external factors on PM To further clarify the relationship between PM and lung disease, clarify the pathogenesis of some lung diseases and its prevention and treatment is of great significance. Alveolar macrophages (AM, the same below) are important components of PM