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目的：比较鼻内镜下两种不同径路手术治疗真菌性上颌窦炎的临床疗效。方法取鼻内镜中鼻道联合下鼻道双径路手术治疗真菌性上颌窦炎（40例）作为治疗组，单纯鼻内镜中鼻道径路手术治疗真菌性上颌窦炎（40例）作为对照组，比较两组术后疗效。结果随访1年，治疗组治愈39例，无效1例；对照组治愈32例，无效8例（χ2＝4．507，P ＜0．05）。结论中、下鼻道联合径路手术治疗真菌性上颌窦炎疗效优于单纯鼻内镜中鼻道径路手术，是一种微创、有效、安全的治疗真菌性上颌窦炎的手术方式。“,”Objective To compare the therapeutic effect of different kinds of endoscopic nasal surgery for fungal maxil-lary sinusitis.Methods 40 patients were treated by endoscopic maxillary sinus surgery in combination with windowing of inferior nasal meatus as the treatment group,and the other 40 patients were treated by the simple endoscopic nasal sur-gery with middle nasal meatus as the control group.Results During a follow up of one year,39 patients were cured and 1 patient had relapse in the treatment group,and 32 patients were cured and 8 patients had relapse in the control group (χ2 =4.507,P <0.05).Conclusion Endoscopic maxillary sinus surgery in combination with windowing of in-ferior nasal meatus is a minimally invasive,effective and safe approach for surgical treatment of fungal maxillary sinuisitis.