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肿瘤细胞的多药耐药是导致肿瘤患者化疗失败的主要原因,针对不同个体制定个体化化疗方案是临床化疗中亟待解决的问题。检测肿瘤细胞耐药基因的表达和药物敏感性将为临床化疗提供有效的帮助。现综述肺癌细胞的体外培养、耐药基因及药物敏感性检测方面的研究进展。
Multidrug resistance of tumor cells is the main reason for the failure of chemotherapy in cancer patients. To formulate individual chemotherapy regimens for different individuals is an urgent problem to be solved in clinical chemotherapy. Detection of tumor cell resistance gene expression and drug sensitivity will provide an effective clinical chemotherapy. The research progress of lung cancer cells in vitro culture, drug resistance genes and drug sensitivity testing are reviewed.