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用动态心电图研究了268例心肌梗塞、心肌缺血、Lown’s Ⅰ～Ⅴ级室早患者QT间期昼夜变化,并与55例正常人对照。结果表明:全部受检者夜间QT间期均延长(P<0.001);QT与RR间期比较,正常组有显著相关,心肌梗塞、心肌缺血、Lown’s Ⅳ、Ⅴ组相关系数依次小于正常组,其夜间QTC明显延长(P<0.001),与正常组比较有显著差异(P<0.01)。提示心肌梗塞、心肌缺血、Lown’s Ⅳ、Ⅴ级室早夜间QT间期延长与植物神经功能受损及心室肌复极不均一有关。
The ambulatory QT interval diurnal changes in 268 patients with myocardial infarction, myocardial ischemia and Lown’s Ⅰ ~ Ⅴ stage ventricular tachycardia were studied by dynamic electrocardiogram and compared with 55 normal controls. The results showed that all patients had prolonged nighttime QT interval (P <0.001). QT and RR interval were significantly correlated with normal group. The correlation coefficients of myocardial infarction and myocardial ischemia in Lown’s Ⅳ and Ⅴ groups were less than those in normal group , QTC significantly prolonged at night (P <0.001), compared with the normal group there was a significant difference (P <0.01). Tip myocardial infarction, myocardial ischemia, Lown’s Ⅳ, Ⅴ room early QT prolongation and autonomic dysfunction and ventricular repolarization heterogeneity related.