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目的观察左卡尼汀治疗不稳定型心绞痛病人的临床疗效。方法选择46例冠心病不稳定型心绞痛伴高脂血症病人,随机分为两组,一组加用布卡尼汀,另一组应用硝酸酯类药物作为对照,服药4周。结果治疗后两组病人每天心绞痛发作次数、硝酸甘油片消耗量比较差异无统计学意义(P>0.05),且两组其值分别较治疗前明显减小,ECG改善情况两组间比较差异无统计学意义。布卡尼汀还降低血总胆固醇、甘油三酯,升高高密度脂蛋白。结论布卡尼汀治疗不稳定型心绞痛疗效肯定,并与硝酸酯类药相似,且可调节血脂水平。
Objective To observe the clinical efficacy of levocarnitine in patients with unstable angina pectoris. Methods Forty-six patients with unstable angina pectoris and hyperlipidemia were randomly divided into two groups, one with bukametin and the other with nitrates. Results After treatment, the incidence of angina pectoris and the consumption of nitroglycerin tablets in the two groups were not significantly different (P> 0.05), and the values of the two groups were significantly decreased compared with those before treatment. The improvement of ECG was no significant difference between the two groups Statistical significance. Bukatainin also lower blood total cholesterol, triglycerides, elevated high density lipoprotein. Conclusions Bukatainin is effective in treating unstable angina pectoris and is similar to nitrates and regulates blood lipid levels.